For example, cDCs could secrete chemokines, such as CXCL8, to recruit Th1-like cells into tumor with the bonding of CXCR2. Additionally, the co-stimulatory ligand TNFSF4 (OX40L) and its receptor TNFRSF4 (OX40) were also highly expressed in cDCs and Th1-like cells, respectively. This evidence concerns the gene CXCL8 and neoplasm.