IL17A and psoriasis: Notably, the AUC values of all identified LPLs except lysophosphatidic acid (LPA) (20:4) were higher than 0.7 in both the PSO/CON comparison and the IXE/PSO comparison, which indicated that these identified LPLs may serve as predictive markers of the efficacy of IL-17A mAb treatment in psoriasis (Fig. S3) (Table S2).