In addition, we analyzed the RNF152 expression in the online Kaplan–Meier Plotter HCC database (http://kmplot.com/), and found that lower RNF152 mRNA level showed marginal unfavorable impact on survival for patients with HCC, indicating a tumor suppressor role of RNF152 in HCC. This evidence concerns the gene RNF152 and hepatocellular carcinoma.