NFKBIA and gastric cancer: Even so, we were able to demonstrate through the use of luciferase reporter assays that the HOXA-AS3 knockdown-dependent inhibition of NF-κB activation was reversed when GC cells overexpressed LTβR or were transfected with a miR-29a-3p inhibitor, and Western blotting further confirmed that these manipulations were sufficient to reverse the HOXA-AS3 knockdown-dependent inhibition of IKKβ, IκBα phosphorylation, and nuclear P65 expression in GC cells.