The risk score of each male GC patient was calculated as follows: risk score = expression level of LCN12 × 0.13933 + expression level of CCL21 × 0.00181 + expression level of RNASE2 × 0.01554 + expression level of CGB5 × 0.01036 + expression level of NRG4 × 0.34521 + expression level of AGTR1 × 0.14512 + expression level of NPR3 × 0.23201. This evidence concerns the gene NRG4 and gastric cancer.