ACE2 rs4240157 (CC + CT, adjusted RR = 2.68, 95% CI 1.36–5.27, P = 0.004), rs4646188 (TT, adjusted RR = 2.56, 95% CI 1.06–6.20, P = 0.037) were correlated with higher risk of CS in participants with T2D during follow-up period, as shown in Table 2. The gene discussed is ACE2; the disease is type 2 diabetes mellitus.