[13] confirmed that 8 ACE2 SNPs (e.g., rs233575, rs879922, rs2074192, rs1978124, rs4646188, rs2048683, rs4646156 and rs4240157) were not only linked to moderate to high risk of T2D but also with higher risk of hypertension and dyslipidemia in Uygur patients with T2D. This evidence concerns the gene ACE2 and metabolic syndrome.