PPARA and schizophrenia: It is also most probable Hcy interruption/disruption plays some significant roles in the co-regulation of some downstream retrotransposons such as transposable elements (TEs), repetitive sequences in mammalian genomes, which have been implicated in many of the same conditions for which PPARα agonists are therapeutic including neuro-degeneration, schizophrenia, and drug addiction.