The most prevalent variant in our cohort was rs1065852 in CYP2D6 (AF = 60.95%), a marker single nucleotide polymorphism (SNP) of a markedly reduced or null allele, while the most prevalent HLA risk allele was HLA-B*15:02 (AF = 9.68%; S6 Table). Here, CYP2D6 is linked to atrial fibrillation.