ASPN and Familial prostate cancer: NT5E, TNC, and PDGFRβ expression were also dually examined in a subset of cases probed for ASPN expression in stroma adjacent to benign prostate (n ≥ 7) and in Gleason grade 3 (n ≥ 4), Gleason grade 4 with noncribriform morphology (n ≥ 6), and Gleason grade 4 with cribriform morphology (n ≥ 5) prostate cancer.