ASPN and Familial prostate cancer: ENG expression was also dually examined in a subset of cases probed for ASPN expression in stroma adjacent to benign prostate (n = 10) and in Gleason grade 3 (n = 6), Gleason grade 4 with noncribriform morphology (n = 7), and Gleason grade 4 with cribriform morphology (n = 6) prostate cancer.