Jeon et al.30 investigatedMDRD, CKD-EPI-cr, and cystatin C levels in normoalbuminuric (n= 332),microalbuminuric (n= 83), and macroalbuminuric (n= 42) type 2 diabetic patients.Similar to our study, MDRD and CKD-EPI eGFRs were found significantly lower in themacroalbuminurics and microalbuminurics than in the normoalbuminurics (p<0.001).The cystatin C levels of serum and urine increased with increasing degree ofalbuminuria. The gene discussed is CST3; the disease is type 2 diabetes mellitus.