A large‐scale network‐based analyses of resting‐state functional magnetic resonance imaging (rfMRI) data showed that increased plasma CRP was associated with reduced functional connectivity in a widely distributed network including ventral striatum, parahippocampal gyrus/amygdala, orbitofrontal and insular cortices, and posterior cingulate cortex in patients with depression (Yin et al., 2019). Here, CRP is linked to depressive symptom measurement.