As G6PD deficiency is associated with both acute and chronic hemolytic anemia (Porter et al, 1964; Miwa & Fujii, 1996) (OMIM #300908), and with malaria resistance (Luzzatto, Usanga, & Reddy, 1969) (OMIM #611162), identifying functionally important residues in G6PD should inform the diagnosis and treatment of G6PD‐associated genetic disorders. The gene discussed is G6PD; the disease is G6PD deficiency.