FGF21 and type 1 diabetes mellitus: In contrast, FGF21 administration did not affect blood glucose (Figure 2G) or bodyweight (Figure 2H) of the T1DM mice within 28 days after HLI induction, which further confirmed that FGF21 can enhance ischaemic angiogenesis and blood perfusion under diabetic conditions independent of its effect in lowering blood glucose and bodyweight.