Apart from TMPRSS2:ERG, which is only present in 20% of AA men versus 62% of CA men,245 most biomarkers considered were more prevalent in AA men, especially in the early stages of oncogenesis (eg, TMPRSS2/ERG translocation/fusions, telomere dysregulation, GSTM1 hypermethylation, and C‐MYC alteration), during the metastatic stage (eg, PTEN loss and telomerase activation) and for castration resistant disease (eg, AR mutation and activation) (Rebbeck, 2016‐9). Here, TMPRSS2 is linked to glycogen storage disease VI.