Prostate adenocarcinoma with diffuse neuroendocrine differentiation (typical prostate acinar adenocarcinoma or prostate ductal adenocarcinoma with at least 1 neuroendocrine marker >50% positive) (Figures 2G–R), and of which 34 cases were matched, 27 cases were AR positive, and 23 cases were PSA positive. This evidence concerns the gene KLK3 and prostatic acinar adenocarcinoma.