All these reports collectively suggest that overexpression of COL11A1 in different cancerous tissues results in metastasis and recurrence of several human cancers (García-Pravia et al., 2013; Vázquez-Villa et al., 2015; Shen et al., 2016; Li A. et al., 2017; Toss et al., 2019). The gene discussed is COL11A1; the disease is cancer.