Further studies have also established that COL11A1 gene attributes as a prognostic biomarker for human carcinoma-associated stromal cells and also stimulates cancer progression in lungs, breast, gastrointestinal tract, and pancreas (García-Pravia et al., 2013; Vázquez-Villa et al., 2015; Shen et al., 2016; Li A. et al., 2017; Toss et al., 2019). This evidence concerns the gene COL11A1 and cancer.