Another study previously screened the profile of chemokines and cytokines produced by adiponectin-stimulated RA effector cells showing that the production of CXCL8, CCL5, TNF, and IL-6 by lymphocytes from healthy subjects, and CXCL1, CXCL5, CXCL8, CCL2, and IL-6 by FLS from patients with RA were significantly increased after adiponectin stimulation (10). The gene discussed is CXCL1; the disease is rheumatoid arthritis.