When comparing biopsies from NAFL (n=2), steatohepatitis (n=3) and healthy (n=4) livers, Lee et al. (89) found that protein levels of LC3A/B-II and ATG16L1 were increased in NAFLD livers with steatohepatitis while other autophagic factors such as LC3A/B-I and p62 were not different. The gene discussed is MAP1LC3A; the disease is metabolic dysfunction-associated steatotic liver disease.