In a recent study, it was shown that haploinsufficiency of OCTN2 in lcFAO disorder mice results in decreased free carnitine levels and subsequently decrease in tissue and plasma LCAC accumulation but does not significantly affect clinically relevant outcome parameters (hypoglycemia, heart weight or liver weight) (Ranea-Robles et al., 2020). The gene discussed is SLC22A5; the disease is Hypoglycemia.