RSV appeared to be protective against neurodegenerative diseases by activating SIRT1, AMPK, and PGC-1α (Baur et al., 2006; Lagouge et al., 2006; Dasgupta and Milbrandt, 2007; Rocha-González et al., 2008). The gene discussed is SIRT1; the disease is neurodegenerative disease.