Most studies on this gene have focused on its role in increasing the resistance of tumor cells to anticancer drugs (Koppaka et al., 2012), assisting ALDH2 in acetaldehyde and ethanol metabolism (Chen et al., 2015), and its high expression representing a poor clinical prognosis of cancer (Rebollido-Rios et al., 2020), as well as its function in protecting intraocular tissues from exposure to UV radiation and reactive oxygen species-induced damage (Chen et al., 2013). Here, ALDH2 is linked to neoplasm.