PRRT2 and Parkinson disease: We next observed that the phosphorylation of PKC/MEK/ERK and NF-κB induced by peripheral LPS injection was largely inhibited by Clo-lipo administration as compared to the PD+PBS lipo+saline+L-dopa group (*p < 0.05, **p < 0.01, vs. PD+saline+L-dopa, #p < 0.05, ###p < 0.001 vs. PD+PBS lipo+LPS+L-dopa, Figures 7A,C, n = 4/group).