Furthermore, the Western blot analysis revealed that administration with Clo-lipos decreased p-NR2B and NR2B expression in the lesioned striatum of the PD+clo lipo+saline+L-dopa group as compared with the PD+PBS lipo+saline+L-dopa group (*p < 0.05, **p < 0.01, ***p < 0.001, vs. PD+saline+L-dopa, #p < 0.05, ##p < 0.01 vs. PD+PBS lipo+LPS+L-dopa, Figures 7A,B, n = 4/group). Here, GRIN2B is linked to Parkinson disease.