PRRT2 and Parkinson disease: Our results demonstrated that the administration of peripheral LPS to the PD rats could significantly increase the phosphorylation of PKC/MEK/ERK and NF-κB compared with the saline-treated PD rats during the course of the L-dopa injection (*p < 0.05, ***p < 0.001 vs. PD+saline+L-dopa, Figure 5, n = 4/group).