The administration of Clo-lipo can inhibit the release of neuroinflammatory cytokines IL-1β, IL-6, and TNF-α in the lesioned striatum compared with the PD+PBS lipo+LPS+L-dopa group (***p < 0.001, vs. PD+ saline +L-dopa, #p < 0.05, vs. PD+PBS lipo+LPS+L-dopa, Figure 6D,n = 4/group). This evidence concerns the gene IL1B and Parkinson disease.