RCL1 may be involved in the response to antipsychotic treatment in schizophrenia [48], and a case-control study has shown that an intergenic SNP variant between the HNRNPA1P41 pseudogene and RCL1 is statistically significantly associated with Alzheimer’s disease (AD) and related dementias (rs9969783 chr9:4,888,441 [hg19], effect size: −0.2949 [unit decrease] std dev: 0.0615 p-value: 1.63E−06) [49]. Here, RCL1 is linked to early-onset autosomal dominant Alzheimer disease.