For example, one study reported that alterations in phosphorylation responses at proinflammatory proteins NF-κB p65 (pS529) and Stat3 (pS727) were shared between conditions with negative symptomatology (schizophrenia and major depression) while aberrant responses to phosphatase inhibitor calyculin A at S6 (pS235/pS236) were shared between conditions with potential psychotic symptomatology (schizophrenia and bipolar disorder)51. The gene discussed is NFKB1; the disease is bipolar disorder.