Both these pairs of cell lines expressed high levels of ILEI and c-MET (Fig. 2c) as compared to control samples from non-metastatic MCF7 and the metastatic MDA-MB-231 human breast cancer cell line lacking FAM3C and MET amplifications but with upregulated ILEI expression as a characteristics of metastatic capacity [4]. The gene discussed is FAM3C; the disease is breast cancer.