In accordance with this, the transcription factor NF-κB (denoted as “Rel” in Additional file 2: Table S2) and several of the inflammatory genes it induces (e.g. Il6, Ccl2, Ccr2, Il1b, Vcam) was upregulated in the NASH-STZ-hamster compared to the NASH group. Here, REL is linked to metabolic dysfunction-associated steatohepatitis.