SNHG3 and esophageal cancer: qRT-PCR showed that SNHG3 was highly expressed and miR-186-5p was lowly expressed in 348 esophageal cancer patients compared with their normal esophageal tissues; moreover, we noticed that SNHG3 expressed highly in recurrent esophageal cancer patients, however, miR-186-5p expressed lowly in recurrent esophageal cancer patients (Fig. 1a–d).