SOX17 and hereditary elliptocytosis: To confirm the role of SOX17 in establishing the HOXA pattern in HE, we evaluated the expression of arterial and HOXA genes in the 3 major subsets of HE on day 5 (Figure 5A), excluding the DLL4−CXCR4+ population, which has a very limited hematopoietic potential (Figures 3F and 3G).