IFNG and bacterial infectious disease: Although immunosenescence is well recognized in the older population [14, 15], there is also evidence that circulating pro and anti-inflammatory cytokines, such as Interleukin-6 (IL-6) and Interferon-Gamma (IFN-g), are uniquely deranged in patients after hip fracture resulting in immunosuppression leading to increased risk of bacterial infections [14–16].