INS and Ovarian Hyperandrogenism: In the whole sample of PCOS and control subjects, correlation analysis revealed that the PTX3 level in FF was positively associated with the existence of PCOS (R = 0.534, P < 0.001), cycle length (R = 0.425, P < 0.001), basal LH to FSH ratio (R = 0.398, P < 0.001), and TT (R = 0.475, P < 0.001) in serum, AFC (R = 0.467, P < 0.001), ovarian insulin level (R = 0.179, P = 0.010), and ovarian hyperandrogenism (R = 0.616 for androstenedione; R = 0.664 for TT; R = 0.668 for FAI, all P < 0.001).