GLP1R and type 2 diabetes mellitus: In a hospital-based Chinese study including obese individuals with poorly controlled type 2 diabetes, the variant T allele of GLP1R rs10305420 (amino acid change: Pro to Leu) was associated with a smaller reduction in HbA1c (4.4 mmol/mol [0.4%]) and body weight (−1.3 kg) after 6 months of exenatide treatment [37].