In PROGNOSIS, the sFlt-1/PlGF ratio has been shown to improve the short-term prediction of preeclampsia in women with clinical suspicion of the condition, and NICE guidelines recommend the use of the sFlt-1/PlGF ratio test to rule out preeclampsia, in addition to standard care, in women between 20 and 34 weeks + 6 days of gestation [35]. This evidence concerns the gene PGF and preeclampsia.