NFKB1 and colitis: Also, miR-494-3p deficiency in differentiated IECs integrated the colonic epithelium with lamina propria (LP) macrophages via activation of the IKKβ/NF-κB pathway, promoting macrophages recruitment, M1 activation, and EDA-A2 secretion in DSS-induced mouse colitis as well as in cultured macrophages.