We also examined the severity of colitis in a 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis model50 using WT and Gp2–/– mice, and the results were consistent with the DSS-induced colitis data (Fig. 4d–h); body weight and colon length analyses showed severe disease in Gp2–/– mice compared with in WT mice (Fig. 4j and Supplementary Fig. 12a). The gene discussed is GP2; the disease is colitis.