The lncRNA lncRNA-LET (lncRNA-low expression in tumor) acts as a competing endogenous RNA of the oncomiR miR-373-3p, and blocks miR-373-3p-mediated Dickkopf-1 (DKK1) and tissue inhibitor of metalloproteinase-2 (TIMP2) down-regulation [58]. This evidence concerns the gene TIMP2 and neoplasm.