In Burkina Faso, genetic epidemiology has demonstrated that the wild-type R131 allele (rs1801274) of the FcγRIIA (CD32) and tumour necrosis factor (TNF)-238G allele (rs361525) were associated with protection from clinical malaria and high parasitaemia, respectively, in infants and children until 10 years of age [27–29]. This evidence concerns the gene TNF and malaria.