NOS2 and malaria: To address this question, 17 single nucleotide polymorphisms (SNPs) in 11 genes of the innate immune system previously associated with malaria-related phenotypes in African populations (including cytokines, TLRs, Fcγ receptors and nitrogen oxide synthase 2, NOS2) [4, 14, 39–42] were selected to investigated its association with malaria susceptibility in infants living in Nanoro (Burkina Faso), using a nested case–control study design.