ACE and obesity due to melanocortin 4 receptor deficiency: Regardless of the variables that constitute the CHA2DS2-VASc scoring system, the study groups were statistically different not only in terms of the consumption of insulin, oral antidiabetic agents, calcium-channel blockers, angiotensin-converting enzyme inhibitors or angiotensin II-receptor blockers, and diuretics but also in regard to left circumflex artery stenosis, single-vessel disease, and obesity.