TRIM21 and dry eye syndrome: In the same report, the passive transfer of SS-A52 immune sera-induced salivary gland dysfunction.[26] In another study, anti–SS-A and anti–SS-B antibodies were detected in the lacrimal fluid, and their presence in the serum or tear fluid was associated with the severity of keratoconjunctivitis sicca.[27] However, the relationship between SS-A antigen and thymic tumors is still unclear.