Low mRNA expression of ARID2 (p=0.0035), ARID4A (p=0.0349), JARID1A (p=0.0473), JARID1D (p=0.0322) and high mRNA expression of JARID1B (p=0.0067), JARID1C (p=0.0407) were interrelated with worse OS in grade II breast cancer patients. The gene discussed is KDM5A; the disease is breast cancer.