The top 5 genes with highest feature important score were selected, namely fanconi anemia complementation group E (FANCE), UTP3 small subunit processome component (UTP3), DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13), ADAM like decysin 1 (ADAMDEC1), and deoxyribonuclease 1 like 3 (DNASE1L3). The gene discussed is DNASE1L3; the disease is anemia.