Instead, metastasis occurred at an even rate between all three expression levels; the metastatic tumor incidence was 23% in ACC subjects with low IL-13Rα2 expression, 20% in ACC subjects with medium IL-13Rα2 expression, and 23% in ACC subjects with high IL-13Rα2 expression (Fig 3A and 3B). The gene discussed is IL13RA2; the disease is adrenal cortex carcinoma.