Consistently, the analysis of publicly accessible Gene Expression Omnibus (GEO) data sets excluded surgery patients demonstrated that the mRNA levels of Lzp in livers from obese and simple hepatic steatosis patients, but not nonalcoholic steatohepatitis (NASH), were also significantly higher than those of healthy controls (Fig 7F and S9 Table). This evidence concerns the gene OIT3 and metabolic dysfunction-associated steatohepatitis.