We next reviewed the expression of HEY1, MYC, and RAD21 in the bulk RNA-seq data between MPNST and the PN for which there was data, and we found these 3 genes to be more highly expressed in MPNST compared with PN (Figure 4D and Supplemental Figure 6), further implicating these as candidate genes. This evidence concerns the gene RAD21 and malignant peripheral nerve sheath tumor.