ANXA5 and metabolic dysfunction-associated steatotic liver disease: To further explore and explain the therapeutic effect of MSCs against cell death, we detected apoptosis by TUNEL assay and Annexin V & PI staining, but there was no obvious apoptosis either in livers of HFD‐fed rats or PA‐treated HepG2 cells (data not shown), whereas our previous studies have reported a programmed cell death known as 'pyroptosis' plays an important role in NAFLD development.32