Supplementary Table S3 contains results from the power analyses for the top genome-wide significant SNPs and HLA alleles in HSP (rs7754768, rs9275578, HLA-DQA1*01:01, HLA-DQB1*05:01, and HLA-DRB1*01:01). The gene discussed is HLA-DRB1; the disease is hereditary spastic paraplegia.