DPP6 and frontotemporal dementia: We also screened DPP6 in AD patients with an onset age ≤ 70 years and in patients with frontotemporal dementia (FTD).We identified an enrichment of rare non-synonymous variants (nonsense, frameshift and missense) in the EOAD cohort (p value = 0.03, OR = 2.21 95% CI 1.05–4.82), and the FTD cohort (p value = 0.006, OR = 2.59, 95% CI 1.28–5.49) [1].