Displacement assays with the selective, reversible MAO-A binder fluorethylharmine and the selective, reversible MAO-B deprenyl binder showed non-measurable affinity of 18F-PI2620 towards MAO-A and MAO-B, excellent binding to tau pathology in AD brain tissue of different Braak stages, and favorable kinetics in rhesus monkey models [26]. Here, MAOB is linked to Alzheimer disease.