Moreover, we have shown for the first time that how the hematological indices range with differences in gestation age in four different α-thalassemia and five different β-thalassemia subgroups, and trends of RBC, Hb, and HCT in three α-thalassemia subgroups (silent carrier, trait, and major) were opposite to those of normal fetuses, while other subgroups were consistent to normal groups. Here, GSTM1 is linked to thalassemia.