For instance, hsa_circ_0005273 serves as a new therapeutic target of metastatic colorectal cancer;14 exosome-transmitted circ_MMP2 facilitates the metastasis of hepatocellular carcinoma15; circ_AMOTL1 accelerates the growth of cervical cancer by regulating AMOTL116. The gene discussed is MMP2; the disease is cervical carcinoma.