TP53BP1 and Fanconi anemia: In addition to regulating cellular processes including metabolism, growth, and survival, GSK3β also mediates the repair of DNA DSBs through phosphorylation of p53 binding protein 1 (53BP1)60 and modulates the HRR pathway by phosphorylating the Fanconi anemia-associated protein (FAAP2), an important component of the Fanconi anemia complex involved in the repair of DNA inter-strand cross-links61.